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Avastin is a drug that keeps blood vessels from growing, it starves the tumor so to speak. if a cancer cell broke off from the mass and went to my liver and tried to set up house there, the avastin would make sure that it couldn't truck any blood in and voila--the tumor dies. The shot is adjunct therapy to the chemo. They wouldn't put me in the hospital for it; i would just get that extra shot along with the chemo. The trial is to see how well a more aggressive approach is tolerated---they are basically using a stage IV protocol on stage 1,2, and 3 tumors.
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