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I can speak from the other side of the coin: I went through a course of almost every anxiety and depression medication around in the late 90s and early 2000s. None of them helped. Some of them made things worse. Others did nothing at all.
What ended up working for me was a diet and exercise regimen (along with therapy). A serious one. I've kept it up non-stop for 5-6 years and have been doing great.
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