Shawnee123,
Download and run the latest BIOS update:
http://support.dell.com/support/down...&catid=&impid=
And this utility to provide better drivers for USB, PCI, and AGP from Intel:
http://downloadcenter.intel.com/T8Cl...Name=&lang=eng
Both of these will help eliminate issues with your USB devices.
Yes, I've used a Dimension 4600 before. It's actually quite a nice machine that has onboard SATA support.