Any controlled medications are supposed to be handed into a pharmacy to be disposed of safely. When Dad died I took back a cardboard box and a carrier bag full of assorted medications. Inhalers, opiates, anti-biotics: all sorts. I didn't even sort through them I just bagged anything that looked like prescription medicine, packaging and all.
The pharmacist asked me if there were any sharps in there, but other than that they'll dispose of all of it, including medical devices (like spacers and inhalers and so on).
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