One piece units usually get nailed right to the studs through the flange. You want to set the base in a large blob of either thinset or this stuff that I can't remember right now. anyway, you use green board where ever sheetrock would be. It has a slightly water resistant paper. You can tile on top of drywall, but only for areas that will stay dry. In a shower you need to use thinset on backerboard. Glatt is right, avoid mastic.
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And now I'm finished posting.
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