If you're talking about two sounds that play on top of one another... That's really hard. If you have a copy of the *exact* sound that you want to get RID of, you can invert that waveform, line it up perfectly with the first audiofile, and the sounds will cancel each other out, in theory leaving you with the sound you want. But the realistic answer is, there's no way to do it even with the fanciest of plugins.
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