The skin on your fingertips gets really thick. Especially on the fretting hand, the left hand, the one pressing down on the strings. You'd think it would be the right hand, which is plucking; and that skin gets thicker too, but not like the left.
Your hands get stronger. You never really think about your hands being strong. But just like anything, you exercise them, they respond.
After working really hard on one section, I noticed the veins in the back of my wrist and hand, sticking way out. They didn't used to do that when I was fatter.
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