Something Positive was my little gem, and still gets a daily read even if the author isn't 100% consistent.
Schlock Mercenary gets hit every day as well. Interesting premise, more amorphism (I hope that isn't a predictor for my future somehow), good interaction with the author, and lots of BLAM!
There are lots more, but the ones that entertain me the most are
Penny Arcade and
MegaTokyo. Each three times a week and a pantload of funny.