[DanaC]

First five mins is a fairly rambling and chaotic intro, but the interview itself is awesome. Richard Herring's award winning Leicester Square Theatre Podcast runs weekly - used to air for free as an audio podcast and you could pay a small amount to download the full filmed version. He's had some excellent guests and the interviews range from silly to serious. Stephen Fry, in his interview, famously admitted to a suicide attempt the previous year.

Here's an excellent and really in depth interview with Ben Goldacre, on bad science, big pharma, use and misue of statistics in public policy making etc: