Breast Cancer Therapy

xoxoxoBruce · 07-29-2014, 02:32 PM

There seems to be a new study every other day which gets trumpeted the big breakthrough in treating this or that. Often it's the result of one study and unrepeatable, but that's part of the research funding rat race.

Science Daily has an interesting one, breast cancer therapy needs dark.

Quote:

Summary:
Exposure to light at night, which shuts off nighttime production of the hormone melatonin, renders breast cancer completely resistant to tamoxifen, a widely used breast cancer drug, says a new study. Melatonin by itself delayed the formation of tumors and significantly slowed their growth, researchers report, but tamoxifen caused a dramatic regression of tumors in animals with either high nighttime levels of melatonin during complete darkness or those receiving melatonin supplementation during dim light at night exposure.

If it proves to be true it's cheap and easy.

glatt · 07-29-2014, 02:59 PM

Now we can supplement our paleo diets with paleo lighting.

orthodoc · 07-30-2014, 04:58 AM

The connection of melatonin levels, exposure to light at night, and circadian rhythm disruption to increased breast cancer risk has been sufficiently established for IARC (the International Agency for Research on Cancer) to have declared circadian rhythm disruption to be a probable human carcinogen (Group 2A).

xoxoxoBruce · 07-30-2014, 11:31 AM

So this is reaffirming an accepted premise. I guess that's a good thing, to bolster evidence for what they believe is true, but makes me wonder why they are spending resources to do this research.

glatt · 07-30-2014, 11:42 AM

What's disappointing is the little detail about how having dim light that is the equivalent of faint light coming under a closed door in a dark room is enough to negate the effects.

How can a modern human live a substantial portion of their life in the pitch dark?

Undertoad · 07-30-2014, 11:49 AM

Did they ever? Moonlight is usually brighter than that, all by itself.

Big Sarge · 07-30-2014, 01:02 PM

maybe we could keep them in caves or down in the basement. naturally this is for their own good

orthodoc · 07-30-2014, 10:05 PM

Naturally.

Or perhaps Thomas Edison, in his quest to ensure that the lazy working class be forced to work beyond sunset, has more to account for than previously suspected ...

07-30-2014, 04:58 AM	#3
orthodoc Not Suspicious, Merely Canadian Join Date: Oct 2006 Posts: 3,774	The connection of melatonin levels, exposure to light at night, and circadian rhythm disruption to increased breast cancer risk has been sufficiently established for IARC (the International Agency for Research on Cancer) to have declared circadian rhythm disruption to be a probable human carcinogen (Group 2A). __________________ The greatness of a nation and its moral progress can be judged by the way its animals are treated. - Ghandi

07-30-2014, 11:31 AM	#4
xoxoxoBruce The future is unwritten Join Date: Oct 2002 Posts: 71,105	So this is reaffirming an accepted premise. I guess that's a good thing, to bolster evidence for what they believe is true, but makes me wonder why they are spending resources to do this research. __________________ The descent of man ~ Nixon, Friedman, Reagan, Trump.

07-30-2014, 01:02 PM	#7
Big Sarge Werepandas - lurking in your shadows Join Date: Jun 2008 Location: In the Deep South Posts: 3,408	maybe we could keep them in caves or down in the basement. naturally this is for their own good __________________ Give a man a match, & he'll be warm for 20 seconds. But toss that man a white phosphorus grenade and he'll be warm for the rest of his life.

07-30-2014, 10:05 PM	#8
orthodoc Not Suspicious, Merely Canadian Join Date: Oct 2006 Posts: 3,774	Naturally. Or perhaps Thomas Edison, in his quest to ensure that the lazy working class be forced to work beyond sunset, has more to account for than previously suspected ... __________________ The greatness of a nation and its moral progress can be judged by the way its animals are treated. - Ghandi

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07-29-2014, 02:59 PM	#2
glatt ™ Join Date: Jul 2003 Location: Arlington, VA Posts: 27,717	Now we can supplement our paleo diets with paleo lighting.

07-30-2014, 11:42 AM	#5
glatt ™ Join Date: Jul 2003 Location: Arlington, VA Posts: 27,717	What's disappointing is the little detail about how having dim light that is the equivalent of faint light coming under a closed door in a dark room is enough to negate the effects. How can a modern human live a substantial portion of their life in the pitch dark?

07-30-2014, 11:49 AM	#6
Undertoad Radical Centrist Join Date: Jan 2001 Location: Cottage of Prussia Posts: 31,423	Did they ever? Moonlight is usually brighter than that, all by itself.

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