Cataract Cure

[xoxoxoBruce]

They may have found a miracle cure for cataracts.

Researchers in the US have developed a new drug that can be delivered directly into the eye via an eye dropper to shrink down and dissolve cataracts - the leading cause of blindness in humans.

While the effects have yet to be tested on humans, the team from the University of California, San Diego hopes to replicate the findings in clinical trials and offer an alternative to the only treatment that’s currently available to cataract patients - painful and often prohibitively expensive surgery

If this is successful they may be able to figure out how to prevent cataracts before they form.

They tested their lanosterol-based eye drops in three types of experiments. They worked with human lens in the lab and saw a decrease in cataract size. They then tested the effects on rabbits, and according to Hanae Armitage at Science Mag, after six days, all but two of their 13 patients had gone from having severe cataracts to mild cataracts or no cataracts at all. Finally, they tested the eye drops on dogs with naturally occurring cataracts. Just like the human lens in the lab and the rabbits, the dogs responded positively to the drug, with severe cataracts shrinking away to nothing, or almost nothing.

The results have been published in Nature.

"This is a really comprehensive and compelling paper - the strongest I’ve seen of its kind in a decade," molecular biologist Jonathan King from the Massachusetts Institute of Technology (MIT) told Armitage. While not affiliated with this study, King has been involved in cataract research for the past 15 years. "They discovered the phenomena and then followed with all of the experiments that you should do - that’s as biologically relevant as you can get."

The next step is for the researchers to figure out exactly how the lanosterol-based eye drops are eliciting this response from the cataract proteins, and to progress their research to human trials.

link

[glatt]

As a 48 year old, I have to say the timing is good. Even if it takes them a decade to get this to market, there is still time for me.

[xoxoxoBruce]

It might take you a decade to save the price. If they're going to step on the eye surgeon's toes, somebody has to pay.

[Spexxvet]

Originally Posted by xoxoxoBruce

It might take you a decade to save the price. If they're going to step on the eye surgeon's toes, somebody has to pay.

Insurance companies (Medicare, primarily) are paying doctors about $700 per eye now, so it's got to compete with that.

There are times when cataract surgery would be preferred. Because the implant is calculated to give good distance vision (typically), a patient may go into surgery a -6.00 and come out a -0.50. That's an incredible lifestyle improvement, without even considering the elimination of the cataract itself.

[lumberjim]

You know why Asians don't get cataracts? They plefer Rincolns.

[Lamplighter]

[Gravdigr]

Originally Posted by lumberjim

You know why Asians don't get cataracts? They plefer Rincolns.

Booooo. Hissboooo.



Had to draw Momdigr a picture. She finally got it.

[Happy Monkey]

Another approach would be to remove all large rocks from the riverbed.

[BigV]

A picture?? How many Cadillacs does she own???