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Old 05-03-2020, 09:49 PM   #11
sexobon
I love it when a plan comes together.
 
Join Date: Oct 2009
Posts: 9,793
Woe is me...

^No one got the irony (sigh).^

I guess I'm the only one here old enough to remember that quinine and its derivatives, like chloroquine, are muscle relaxants. Decades ago, quinine and vitamin E (to increase circulation) were combined to treat restless leg syndrome and sold over the counter.

The quinine dose was about 1/10 the therapeutic dose used as an antimalarial. Overdosing on it as a muscle relaxant could lead to the same adverse side affects and risks associated with the dosage for antimalarial use; so, the FDA restricted it back in the '90s. It's still used, by prescription, to treat chloroquine resistant strains of malaria which have mutated so much that they've come full circle and are susceptible to the original quinine treatment again.

I thought it was funny that the drug Trump touted as a possible anti-coronavirus treatment; but, was largely a big fail, could actually be applicable in this situation. These days, no doctor would prescribe it as a muscle relaxant though.
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